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*= key reference

*MacNevin, C.J., Watanabe, T., Weitzman, M., Gulyani, A., Fuehrer, S., Pinkin, N.K., Tian, X., Liu, F., Jin, J., and Hahn, K.M. Membrane-Permeant, Environment-Sensitive Dyes Generate Biosensors within Living Cells. J. Am. Chem. Soc., 141(18): 7275-7282., 2019. PMC6572722. Online article | Free PMC article

Ye, F., Yang, C., Kim, J., MacNevin, C.J., Hahn, K.M., Park, D., Ginsberg, M.H., and Kim, C. Epigallocatechin Gallate Has Pleiotropic Effects on Transmembrane Signaling by Altering the Embedding of Transmembrane Domains. J. Biol. Chem., 292(24): 2858-2864, 2017. PMC5473239 Online article | Free PMC article

*MacNevin, C.J., Toutchkine, A., Marston, D.J., Hsu, C.W., Tsygankov, D., Li, L., Liu, B., Qi, T., Nguyen, D.V., and Hahn, K.M. Ratiometric imaging using a single dye enables simultaneous visualization of Rac1 and Cdc42 activation. J. Am. Chem. Soc., 138(8): 2571-2575, 2016. PMC4825053. Online article | Free PMC article

Helassa, N., Garnett, J.P., Farrant, M., Khan, F., Pickup, J.C., Hahn, K.M., MacNevin, C.J., Tarran, R., and Baines, D.L. A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration. Biochem. J., 464(2):213-20, 2014. PMC4357280. Online article | Free PMC article

Konze, K.D., Ma, A., Li, F., Barsyte-Lovejoy, D., Parton, T., Macnevin, C.J., Liu, F., Gao, C., Huang, X.P., Kuznetsova, E., Rougie, M., Jiang, A., Pattenden, S.G., Norris, J.L., James, L.I., Roth, B.L., Brown, P.J., Frye, S.V., Arrowsmith, C.H., Hahn, K.M., Wang, G.G., Vedadi, M. and Jin, J. An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1. ACS Chem. Biol., 8(6): 1324–1334, 2013. PMC3773059. Online article | Free PMC article

Kummer, L., Hsu, C.W., Dagliyan, O., MacNevin, C., Kaufholz, M., Zimmermann, B., Dokholyan, N.V., Hahn, K.M., and Plückthun, A.  Knowledge-Based Design of a Biosensor to Quantify Localized ERK Activation in Living Cells.  Chem. Biol., 20(6): 847-56, 2013. PMC4154710. Online article | Free PMC article

*Gulyani, A., Vitriol, E., Allen, R., Wu, J., Gremyachinskiy, D., Lewis, S., Dewar, B., Graves, L.M., Kay, B.K., Kuhlman, B., Elston, T. and Hahn, K.M.  A biosensor generated via high-throughput screening quantifies cell edge Src dynamics. Nature Chem. Biol., 7: 437-444, 2011. PMC3135387. Online article | Free PMC article

Garrett, S.C., Hodgson, L., Rybin, A., Toutchkine, A., Hahn, K.M., Lawrence, D.S., and Bresnick, A.R. A Biosensor of S100A4 Metastasis Factor Activation: Inhibitor screening and Cellular Activation Dynamics. Biochemistry, 47:986-996, 2008. PMC3227476. Online article | Free PMC article

*Nalbant, P., Hodgson, L., Kraynov, V., Toutchkine, A., and Hahn, K.M. Activation of endogenous Cdc42 visualized in living cells. Science, 305: 1615-1619, 2004. Onilne article | PDF

Bark, S. J., and Hahn, K.M. Fluorescent indicators of peptide cleavage inside living cells. Methods, 20: 429-435, 2000. Online article | PDF

Hahn, K.M., Conrad, P.A., Chao, J., Taylor, D.L., and Waggoner, A.S.  A photocross-linking, fluorescent indicator of mitochondrial membrane potential.  J. Histochem. Cytochem., 41: 631-634, 1993. Online article | PDF

*Hahn, K.M., DeBiasio, R. and Taylor, D.L. Patterns of elevated free calcium and calmodulin activation in living cells.  Nature, 359: 736-738, 1992. Online article | PDF

Hahn, K.M., Waggoner A.S., and Taylor, D.L. A calcium-sensitive fluorescent analog of calmodulin based on a novel calmodulin- binding fluorophore. J. Biol. Chem., 265: 20335-20345, 1990. Online article | PDF

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~ Updated 04/14/2021