hahn lab

positions available

Applications from creative and ambitious scientists are always welcome. Please send a CV and letter describing your plans and goals to khahn[at]med.unc.edu. We are especially interested in the following areas right now:

Protein engineering, screening and cell biology. We have multiple openings for people interested in protein engineering, e.g. focusing on engineered allosteric control, novel optogenetic approaches and development of molecules to harness cutting edge imaging techniques. The successful candidate will develop new approaches and put them to use in cell biology studies, exploring new areas made accessible by the techniques we will develop. Some projects will be based on high throughput protein screening, so experience there would be valuable.

Synthetic chemistry and cell biology. We are focusing on developing novel dyes and small molecules to examine the conformational changes and other aspects of proteins in live cells and animals. This work will be an opportunity for an experienced synthetic chemist to branch into biology.

Lab manager and protein engineering technician. The person in this position will support the laboratory with molecular biology, protein engineering and management responsibilities. The successful candidate will focus on generating DNA constructs and proteins for  the lab,  and testing hypotheses re the performance of new engineered proteins using  spectroscopy and biochemical techniques. They will help Dr. Hahn manage the lab and  maintain  lab organization, including oversight of purchasing, maintening DNA construct libraries, and managing work study students.

Microscopy Postdoc. We are looking for a postdoctoral fellow who wants to focus on the design and application of cutting edge microscopy for use with unique proteins and dyes we have developed. We are especially interested in single particle tracking, both in 2D and 3D, and in implementing live cell super-resolution techniques using our novel dyes.  This position is an opportunity for an experienced optical scientist with a background in microscope design and automation to apply their knowledge to cell biology, and/or to become involved with design and application of novel molecules. Some microscopes are being built in collaboration with the Superfine and Legant groups at UNC (atomic force and  LLSM). Candidates with appropriate experience from any field are encouraged to apply.

Microscopy Staff Scientist. We are seeking a permanent employee to help us build and maintain cutting edge microscopes, and to participate in research using these microscopes with biosensors, optogenetics, and other unique molecules developed for imaging. In addition to our independent work, we collaborate closely with several laboratories working on optical physics (Superfine, Legant labs at UNC). You would be a bridge between us and these collaborators. We have or are currently pursuing capabilities for single particle tracking in live cells (2D and 3D), 2 photon optogenetics, multiplexed optogenetics and biosensors, lattice light sheet microscopy, and SIM-TIRF.  Candidates with appropriate experience, and education ranging from Bachelor’s to PhD degrees, are encouraged to apply. Your level of responsibility and independence will depend on your initiative and ability.  Salary will be commensurate with experience.
Please send your CV and a cover letter to Dr Klaus Hahn at khahn@med.unc.edu.  

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