hahn lab

cytoskeletal / adhesion signaling and structure

Back to main pubs page

Herron, J.C., Hu, S., Liu, B., Watanabe, T., Hahn, K.M., and Elston, T.C. Spatial models of pattern formation during phagocytosis. PLoS Comput Biol. 18(10): e1010092, 2022. PMC9560619. Open Access online article | Free PMC article

Herron, J.C., Hu, S., Watanabe, T.,  Nogueira, A.T., Liu, B., Kern, M.E., Aaron, J.,  Taylor, A., Pablo, M., Chew, T-L., Elston, T.C., and Hahn, K.M. Actin nano-architecture of phagocytic podosomes. Nature Communications, 13: 4363, 2022. PMC9329332. Free online article | Free PMC article

Liu, B., Stone, O.J., Pablo, M., Herron, C.J., Nogueira, A.T., Dagliyan, O., Grimm, J.B., Lavis, L.D., Elston, T.C., and Hahn, K.M. Biosensors based on peptide exposure show single molecule conformations in live cells. Cell, 184(22): 5670-5685, 2021. PMC8556369. Online article | Free PMC article

Padhi, A., Singh, K., Franco-Barraza, J., Marston, D.J., Cukierman, E., Hahn, K.M., Kapania, R.K., and Nain, A.S.  Force-exerting lateral protrusions in fibroblastic cell contraction. Communications Biology, 3: 390, 2020. PMC7374753. Online article | Free PMC article

Stefanini, L., Lee, R.H., Paul, D.S., O'Shaughnessy, E.C., Ghalloussi, D., Jones, C.I., Boulaftali, Y., Poe, K.O., Piatt, R., Kechele, D.O., Caron, K.M., Hahn, K.M., Gibbins, J.M., and Bergmeier, W. Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood, 132(18):1951-1962m 2018. PMC6213319. Online article | Free PMC article

Takano, T., Wu, M., Nakamuta, S., Naoki, H., Ishizawa, N., Namba, T., Watanabe, T., Xu, C., Hamaguch i, T., Yura, Y., Amano, M., Hahn, K.M. and Kaibuchi, K. Discovery of long-range inhibitory signaling to ensure 0.3 single axon formation. Nature Communications, 8(1):33, 2017. PMC5484694. Online article | Free PMC article

Ye, F., Yang, C., Kim, J., MacNevin, C.J., Hahn, K.M., Park, D., Ginsberg, M.H., and Kim, C. Epigallocatechin Gallate Has Pleiotropic Effects on Transmembrane Signaling by Altering the Embedding of Transmembrane Domains. J. Biol. Chem., 292(24): 2858-2864, 2017. PMC5473239 Online article | Free PMC article

Yi, J.J., Berrios, J., Newbern, J.M., Snider, W.D., Philpot, B.D., Hahn, K.M., and Zylka, M.J. An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A. Cell, 162(4):795-807, 2015. PMC4537845. Online article | Free PMC article

Chu, P-H., Tsygankov, D., Berginski, M.E., Dagliyan, O., Gomez, S.M., Elston, T.C., Karginov, A.V. and Hahn, K.M. Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proc. Natl. Acad. Sci. U.S.A.,111(34): 12420–12425, 2014. PMC4151743. Online article | Free PMC article

Karginov, A., Tsygankov, D., Berginski, M., Chu, P-H., Trudeau, E., Yi, J.J., Gomez, Shawn, Elston, T.C. and Hahn, K.M. Dissecting motility signaling through activation of specific Src-effector complexes. Nature Chem. Bio., 10(4):286-90, 2014.  PMC4064790. Online article | Free PMC article

Galic, M., Jeong, S., Tsai, F-C., Joubert, L-M., Wu, Y.I., Hahn, K.M., Cui, Y. and Meyer, T. External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane. Nature Cell Biol., 14(8): 874-881, 2012.  PMC3519285. Online article | Free PMC article

Garrett, S.C., Hodgson, L., Rybin, A., Toutchkine, A., Hahn, K.M., Lawrence, D.S., and Bresnick, A.R. A Biosensor of S100A4 Metastasis Factor Activation: Inhibitor screening and Cellular Activation Dynamics. Biochemistry, 47:986-996, 2008. PMC3227476. Online article | Free PMC article

Cai, X., Lietha, D., Ceccarelli, D.F., Karginov, A.V., Rajfur, Z., Jacobson, K., Hahn, K.M., Eck, M.J. and Schaller, M.D. Spatial and temporal regulation of focal adhesion kinase activity in living cells. Mol. Cell Biol., 28: 201-214, 2008. PMC2223290. Online article | Free PMC article

Nakamura, K., Uhilk, M.T., Johnson, N.L., Hahn, K.M. and Johnson, G.L. PB1 domain-dependent signaling complex is required for extracellular signal-regulated kinase 5 activation. Mol. Cell Biol., 26: 2065-2079, 2006. PMC1430298. Online article | Free PMC article

Subauste, M., Nalbant, P., Adamson, E. and Hahn, K.M. Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein a-Catenin with the scaffolding protein MAGI-2. J. Biol. Chem., 165: 371-381, 2005. Online article

Subauste, M., Pertz, O., Adamson, E., Turner, C.E., Junger, S. and Hahn, K.M. Vinculin modulation of Paxillin-FAK interactions regulates ERK to control survival and motility. J. Cell Biol., 165: 171-181, 2004. PMC2172187. Online article | Free PMC article

Nishimura, N., Pluttner, H., Hahn, K.M. and Balch, W.E. The δ subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surface. Proc. Natl. Acad. Sci. U.S.A., 99: 6755-6760, 2002. Online article | Free PMC article

Frosst, P., Guan, T., Subauste, C., Hahn, K.M. and Gerace, L. Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export. J. Cell Biol., 156: 617-630, 2002. PMC2174070. Online article | Free PMC article

Subauste, C., List, B., Guan, X., Hahn, K.M., Lerner, R. and Gilula, N.B. A catalytic antibody produces fluorescent tracers of gap junction communication in living cells. J. Biol. Chem., 276: 49164-49168, 2001. Online article | PDF

Weiss, T.S., Chamberlain, C.E., Takeda, T., Lin, P., Hahn, K.M. and Farquhar, M.G. Galpha i3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins. Proc. Natl. Acad. Sci. U.S.A., 98: 14961-14966, 2001. PMC64966. Online article | PMC Free article

Kiosses, W.B., Hahn, K.M., Giannelli, G. and Quaranta, V.  Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: Comparison with breast cancer cell line MCF7.  Cell Adhes. Commun.,8: 29-44, 2001. PDF

Stupack, D.G., Li, E., Kehler, J.A., Geahlen, R.A., Hahn, K.M., Nemerow, G.R. and Cheresh, D.A. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase. J. Cell Biol., 144: 777-787, 1999. PMC2132930. Online article | Free PMC article

Nishimura, N., Bannykh, S., Slabaugh, S., Matteson, J., Hahn, K.M. and Balch, W.E. The Di-acidic (DxE) code found in the cytoplasmic domain of cargo directs concentration during export from the endoplasmic reticulum. J. Biol. Chem., 274: 15937-15946, 1999. Online article | PDF

Shelby, R.D, Hahn, K.M. and Sullivan, K.F. Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells. J. Cell Biol., 135: 545-557, 1996. PMC2121065. Online article | Free PMC article

Waters, J.B., Oldstone, M.B.A. and Hahn, K.M. Changes in the cytoplasmic structure of cytotoxic T lymphocytes during target cell recognition and killing. J. Immunology, 157: 3396-3403, 1996. Online article | PDF

Lewicki, H., Tishon, A., Borrow, P., Evans, C.F., Gairin, J.E., Hahn, K.M., Jewell, D.A., Wilson., I.A. and Oldstone, M.B.A. CTL escape viral variants.  I.  Generation and molecular characterization. Virology, 210: 29-40, 1995. Online article | PDF

Bark, I.C., Hahn, K.M., Ryabinin, A.E. and Wilson, M.C. Differential expression of SNAP-25 protein isoforms during divergent vesicle fusion events of neuronal development. Proc. Natl. Acad. Sci. U.S.A., 92: 1510-1514, 1995. PMC42549. Online article | Free PMC article

Hahn, K.M., DeBiasio, R., Tishon, A., Lewicki, H., Gairin, J.E., LaRocca, G., Taylor, D.L. and Oldstone, M.B.A. Antigen presentation and cytotoxic T lymphocyte killing studied in individual, living cells. Virology, 201: 330-340, 1994. Online article

Hahn, K.M., DeBiasio, R. and Taylor, D.L. Patterns of elevated free calcium and calmodulin activation in living cells.  Nature, 359: 736-738, 1992. Online article | PDF

Hahn, K.M., Humphries, W.G., Helms, A.M., Hastie, S.B. and Macdonald, T.L. Structural requirements for the binding of colchicine analogs to tubulin: the role of the C-10 substituent. Biomed. Chem. Lett., 1: 471-476, 1991. PDF

Back to top
Back to main pubs page


© UNC Department of Pharmacology